Capillary leak syndrome in a 5-month-old infant associated with intractable diarrhoea.

[systemic capillary leak syndrome]

Systemic capillary leak syndrome (SCLS ) is a rare disorder of unknown pathophysiology , characterised by episodic life-threatening hypotension , haemoconcentration and hypo-albuminaemia . A 5 -month -old child presented with episodes of relapsing diarrhoea , vomiting and hyponatraemia and developed generalised oedema during treatment . Clinical and laboratory findings were consistent with acute SCLS . Treatment with careful fluid replacement , fresh frozen plasma and aminophylline in the acute phase and teophylline and gingko biloba in the chronic phase led to sustained remission during follow-up for over 1 year . To our knowledge , this is the youngest case of SCLS in the literature and is unusual in that it presented with diarrhoea .