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Synchronized changes in serum vascular endothelial growth factor during the clinical course of chronic systemic capillary leak syndrome.
[systemic capillary leak syndrome]
Systemic
capillary
leak
syndrome
(
SCLS
)
is
a
rare
disease
characterized
by
leakage
of
plasma
from
blood
vessels
into
the
interstitial
space
due
to
increased
capillary
permeability
.
We
describe
a
24
-
year
-old
man
who
was
hospitalized
with
systemic
edema
,
hypoalbuminemia
,
and
disseminated
intravascular
coagulation
.
After
extensive
investigative
procedures
,
he
was
diagnosed
with
chronic
SCLS
and
made
a
gradual
recovery
after
starting
on
prednisolone
,
terbutaline
,
and
theophylline
.
We
measured
the
patient
's
serum
vascular
endothelial
growth
factor
(
VEGF
)
over
time
and
found
a
relationship
between
serum
VEGF
and
the
clinical
course
.
Diseases
Validation
Diseases presenting
"growth factor"
symptom
22q11.2 deletion syndrome
achondroplasia
adrenal incidentaloma
aniridia
cadasil
cholangiocarcinoma
coats disease
dedifferentiated liposarcoma
dentin dysplasia
dentinogenesis imperfecta
dystrophic epidermolysis bullosa
esophageal carcinoma
esophageal squamous cell carcinoma
hodgkin lymphoma, classical
holt-oram syndrome
inclusion body myositis
kallmann syndrome
krabbe disease
liposarcoma
lymphangioleiomyomatosis
oculocutaneous albinism
oral submucous fibrosis
pleomorphic liposarcoma
primary effusion lymphoma
primary hyperoxaluria type 1
severe combined immunodeficiency
systemic capillary leak syndrome
von hippel-lindau disease
wolf-hirschhorn syndrome
x-linked adrenoleukodystrophy
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