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Synchronized changes in serum vascular endothelial growth factor during the clinical course of chronic systemic capillary leak syndrome.
[systemic capillary leak syndrome]
Systemic
capillary
leak
syndrome
(
SCLS
)
is
a
rare
disease
characterized
by
leakage
of
plasma
from
blood
vessels
into
the
interstitial
space
due
to
increased
capillary
permeability
.
We
describe
a
24
-
year
-old
man
who
was
hospitalized
with
systemic
edema
,
hypoalbuminemia
,
and
disseminated
intravascular
coagulation
.
After
extensive
investigative
procedures
,
he
was
diagnosed
with
chronic
SCLS
and
made
a
gradual
recovery
after
starting
on
prednisolone
,
terbutaline
,
and
theophylline
.
We
measured
the
patient
's
serum
vascular
endothelial
growth
factor
(
VEGF
)
over
time
and
found
a
relationship
between
serum
VEGF
and
the
clinical
course
.
Diseases
Validation
Diseases presenting
"disseminated intravascular coagulation. after extensive investigative procedures"
symptom
systemic capillary leak syndrome
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