Four-limb compartment syndrome associated with the systemic capillary leak syndrome.

[systemic capillary leak syndrome]

Systemic capillary leak syndrome , or the Clarkson syndrome , is an extremely rare condition in which increased capillary permeability results in a massive shift of fluid into the extravascular space . This is followed rapidly by hypotensive shock , haemoconcentration , and , potentially , substantial oedema of the limbs resulting in an acute compartment syndrome . It is important for orthopaedic surgeons to be aware of this syndrome as our medical colleagues , who initially care for these patients , are less familiar with the diagnosis and the need for emergency management of the associated compartment syndrome should it develop . There have been fewer than 100 cases of this entity reported . This case report is the first to describe the subsequent development of a compartment syndrome in all four limbs . Clinical vigilance and continuous monitoring of intracompartmental pressure is necessary in these patients in order to help reduce limb -threatening complications .