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Systemic Capillary Leak Syndrome as an Initial Presentation of ALK-Negative Anaplastic Large Cell Lymphoma.
[systemic capillary leak syndrome]
Systemic
capillary
leak
syndrome
(
SCLS
)
is
a
rare
disease
characterized
by
third
spacing
of
plasma
into
the
extravascular
compartment
,
leading
to
anasarca
,
hemoconcentration
,
and
hypovolemic
shock
.
It
has
been
rarely
associated
with
lymphomas
,
and
reports
usually
indicate
that
it
occurs
after
antineoplastic
treatment
.
We
present
the
case
of
a
patient
with
ALK-negative
anaplastic
large
cell
lymphoma
who
presented
with
SCLS
as
the
initial
manifestation
of
her
lymphoma
.
The
SCLS
resolved
with
treatment
of
the
malignancy
with
steroids
and
chemotherapy
.
