Cerebral blood flow-SPECT in a patient with Sneddon's syndrome.

[sneddon syndrome]

We report a 50 -year -old woman diagnosed with Sneddon 's syndrome and examined by CBF scintigraphy several times for follow-up of the disease . There were no significant changes in her CBF scintigraphic findings or neurological status during the 6 -year follow-up period . Sneddon 's syndrome is a slowly progressive disorder in which livedo reticularis precedes cerebrovascular accidents . Because small cortical arteries are predominantly affected in Sneddon 's syndrome , MR and conventional angiography often fail to show any abnormal findings , and MR imaging may not visualize decreased CBF in the early stage . Therefore , CBF scintigraphy should be performed in patients who have or are suspected of having Sneddon 's syndrome .