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Antibodies to prothrombin in patients with Sneddon's syndrome.
[sneddon syndrome]
Antiprothrombin
antibodies
(
aPT
)
,
a
new
serologic
marker
of
antiphospholipid
syndrome
,
were
studied
in
46
patients
randomly
selected
from
73
with
Sneddon
's
syndrome
and
20
matched
normal
controls
.
aPT
were
elevated
in
26
patients
(
57
%
)
and
were
not
found
in
any
of
the
controls
.
The
addition
of
aPT
data
increased
the
proportion
of
Sneddon
's
syndrome
patients
with
at
least
one
type
of
antiphospholipid
syndrome
marker
from
65
to
78
%
.
The
finding
that
aPT
are
common
in
Sneddon
's
syndrome
supports
the
hypothesis
that
Sneddon
's
syndrome
is
a
form
of
antiphospholipid
syndrome
.
Diseases
Validation
Diseases presenting
"and"
symptom
achondroplasia
adrenomyeloneuropathy
aniridia
carcinoma of the gallbladder
cutaneous mastocytosis
cystinuria
esophageal squamous cell carcinoma
harlequin ichthyosis
hodgkin lymphoma, classical
hydrocephalus with stenosis of the aqueduct of sylvius
kallmann syndrome
liposarcoma
locked-in syndrome
neonatal adrenoleukodystrophy
omenn syndrome
oral submucous fibrosis
pleomorphic liposarcoma
primary hyperoxaluria type 1
proteus syndrome
pyomyositis
pyruvate dehydrogenase deficiency
sneddon syndrome
triple a syndrome
trochlear dysplasia
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