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Familial inflammatory Sneddon's syndrome-case report and review of the literature.
[sneddon syndrome]
Sneddon
's
syndrome
(
SNS
)
which
originally
was
a
clinical
diagnosis
,
is
now
regarded
as
a
common
clinical
manifestation
of
different
disease
entities
.
It
has
been
divided
into
idiopathic
,
autoimmune
and
thromboembolic
subsets
or
in
systemic
lupus
erythematosus
(
SLE
)
-
associated
,
antiphospholipid
syndrome
(
APS
)
-
associated
and
primary
forms
.
Familial
occurrence
of
Sneddon
's
syndrome
is
rare
.
We
present
a
familial
case
of
Sneddon
's
syndrome
with
inflammatory
disease
pattern
,
early
disease
onset
and
association
with
autoimmune
thyroid
disease
and
anticardiolipin
antibodies
.
Although
most
authors
reporting
on
adult
cases
of
SNS
consider
it
a
non-
inflammatory
,
thromboembolic
process
,
the
study
of
cases
with
early
onset
brings
attention
to
the
possible
inflammatory
origin
of
the
syndrome
.
Diseases
Validation
Diseases presenting
"early disease onset and association with autoimmune thyroid disease and anticardiolipin antibodies"
symptom
sneddon syndrome
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