Tremor as the first neurological manifestation of Sneddon's syndrome.

[sneddon syndrome]

We report on a 54 -year -old woman with Sneddon 's syndrome manifested by livedo reticularis , fetal losses , hypertension , and high antinuclear antibody titres . At the age of 42 years she developed tremor of the trunk , limbs , and head only in the standing position that interfered with walking , followed some years later by cognitive decline and a parkinsonian syndrome . T 2 -weighted brain magnetic resonance imaging showed high signal in cortical areas , basal ganglia , midbrain , and cerebellum .

Diseases
Validation

Diseases presenting "cognitive decline" symptom

cadasil

gm1 gangliosidosis

hereditary cerebral hemorrhage with amyloidosis

homocystinuria without methylmalonic aciduria

inclusion body myositis

krabbe disease

oculocutaneous albinism

sneddon syndrome

wolf-hirschhorn syndrome

This symptom has already been validated