Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
[Neurological appearances of primary antiphospholipid syndrome].
[sneddon syndrome]
Neurological
disturbances
frequently
emerge
in
antiphospholipid
syndrome
(
APS
)
.
One
hundred
and
twenty
four
patients
(
100
women
,
24
men
,
mean
age
37
.
5
+
/
-
11
.
3
years
)
with
primary
APS
(
PAPS
)
,
including
76
patients
with
Sneddon
's
syndrome
and
positive
antibodies
to
phospholipids
(
aPL
)
,
have
been
studied
.
A
structure
of
neurological
disturbances
was
as
follows
:
ischemic
lesions
of
cerebral
blood
flow
(
LCBF
)
which
comprised
stroke
and
transient
LCBF
(
91
%
)
;
thrombosis
of
brain
venous
sinuses
(
3
%
)
;
epileptic
seizures
(
24
%
)
;
headache
(
65
%
)
;
chorea
(
15
%
)
;
visual
neuropathy
(
9
%
)
;
peripheral
neuropathy
(
6
%
)
;
multiple
-
sclerosis
-like
syndrome
(
10
%
)
;
myasthenia
syndrome
(
1
%
)
;
syndrome
of
parkinsonism
of
non-
vascular
genesis
(
1
%
)
and
psychotic
disorders
(
2
%
)
.
84
%
patients
had
main
systemic
APS
symptoms
(
fetal
loss
,
thrombosis
)
,
which
preceded
neurological
appearances
in
78
%
cases
.
All
the
patients
had
aPL
:
aPL
to
cardiolipin
(
aCL
)
and
/
or
lupus
coagulant
(
LC
)
and
/
or
aPL
to
phosphatidyl
serine
,
phosphatidyl
inositol
,
phosphatidyl
ethanolamine
.
In
some
patients
,
aCL
titres
ranged
from
positive
to
negative
values
and
LC
was
not
consistently
detected
.
Thus
,
the
presence
of
clinical
symptoms
of
PAPS
including
neurological
disturbances
demands
an
investigation
of
different
aPL
types
as
well
as
a
replicate
study
for
immunological
confirmation
of
PAPS
.
Diseases
Validation
Diseases presenting
"transient lcbf"
symptom
sneddon syndrome
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom