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[Sneddon syndrome with anti-mitochondrial type M5 antibodies].
[sneddon syndrome]
Antimitochondrial
type
M
5
antibodies
(
AMA
-M
5
)
are
among
the
immunological
abnormalities
associated
with
Sneddon
syndrome
.
A
45
year
-old
woman
,
hospitalized
for
diplopia
and
with
a
20
-
year
history
of
obstetrical
accidents
,
internuclear
ophthalmoplegia
and
livedo
,
was
diagnosed
with
Sneddon
syndrome
associated
with
primary
antiphospholipid
syndrome
(
APS
)
aggravated
by
the
presence
of
AMA
-M
5
.
AMA
-M
5
are
immunological
markers
of
APS
to
the
same
extent
as
antiphospholipid
antibodies
.
This
case
demonstrates
the
interest
of
screening
for
AMA
-M
5
in
cases
of
strong
clinical
suspicion
of
APS
when
the
anticoagulant
lupus
test
is
normal
and
no
anti-cardiolipin
,
anti-
b
2
glycoprotein
I
or
antiprothrombin
antibodies
are
found
.
Diseases
Validation
Diseases presenting
"primary antiphospholipid syndrome"
symptom
sneddon syndrome
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