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Atypical movement disorders in antiphospholipid syndrome.
[sneddon syndrome]
Movement
disorders
have
only
rarely
been
reported
in
association
with
antiphospholipid
syndrome
(
APS
)
.
In
such
cases
,
chorea
is
the
most
common
disorder
observed
,
with
occasional
reports
of
hemidystonia
,
Parkinsonism
,
and
hemiballism
.
We
report
here
on
3
cases
of
APS
(
3
women
ages
16
,
46
,
and
56
years
)
who
presented
with
movement
disorders
,
including
tics
,
tremor
,
myoclonus
,
and
a
corticobasal
syndrome
,
never
or
rarely
reported
in
association
with
this
disease
.
Mild
executive
dysfunction
was
observed
in
all
3
patients
.
We
also
report
the
successful
treatment
of
two
of
these
patients
with
mild
oral
anticoagulation
(
INR
2
-
3
)
.
Movement
disorders
in
APS
seem
more
clinically
heterogeneous
than
previously
thought
.
Oral
anticoagulation
should
be
considered
in
the
treatment
of
movement
disorders
associated
with
APS
.
Diseases
Validation
Diseases presenting
"common disorder"
symptom
aniridia
congenital adrenal hyperplasia
cutaneous mastocytosis
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
familial hypocalciuric hypercalcemia
sneddon syndrome
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