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[Sneddon's syndrome: 15 cases with cerebral angiography].
[sneddon syndrome]
Sneddon
's
syndrome
is
a
rare
disease
defined
by
the
presence
of
ischemic
cerebrovascular
events
associated
with
livedo
reticularis
.
We
report
a
retrospective
study
of
fifteen
cases
,
thirteen
women
and
two
men
,
mean
age
of
37
.
93
+
/
-
9
.
77
years
.
All
patients
presented
one
or
more
cerebral
infarcts
.
Six
patients
had
dementia
.
Brain
magnetic
resonance
imaging
showed
several
cortical
infarcts
with
white
matter
involvement
.
Cerebral
angiography
performed
in
all
patients
,
showed
a
distal
arteriopathy
in
twelve
and
thrombosis
of
the
right
carotid
internal
artery
in
one
.
One
patient
had
antiphospholipid
antibodies
.
Ten
patients
were
treated
with
antiplatelet
agents
and
five
with
anticoagulants
.
The
course
was
favorable
in
eight
patients
and
stationary
in
three
.
Four
patients
had
several
recurrent
infarcts
,
one
when
anticoagulants
were
discontinued
,
one
taking
an
anti-sludge-
platelet
agent
and
two
who
were
not
initially
taking
any
treatment
.
Diseases
Validation
Diseases presenting
"dementia"
symptom
adrenomyeloneuropathy
alexander disease
cadasil
canavan disease
carcinoma of the gallbladder
cushing syndrome
gm1 gangliosidosis
hereditary cerebral hemorrhage with amyloidosis
homocystinuria without methylmalonic aciduria
hydrocephalus with stenosis of the aqueduct of sylvius
inclusion body myositis
phenylketonuria
sneddon syndrome
x-linked adrenoleukodystrophy
This symptom has already been validated