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[Dermatologic aspects of anticoagulation].
[sneddon syndrome]
The
coagulation
system
protects
the
body
from
uncontrolled
blood
loss
by
means
of
highly
regulated
processes
.
In
case
of
an
injury
the
coagulation
system
instantly
switches
from
controlled
blood
flow
to
acute
coagulation
and
thrombus
formation
with
the
goal
of
stopping
the
blood
loss
.
Minor
changes
in
this
well-maintained
equilibrium
of
coagulation
and
blood
flow
tip
the
balance
towards
uncontrolled
blood
loss
or
even
fatal
thromboembolic
events
.
Iatrogenic
manipulation
of
this
highly
regulated
system
is
possible
with
a
variety
of
therapeutic
agents
.
We
review
the
basics
of
coagulation
physiology
and
then
discuss
dermatologically
relevant
aspects
of
thrombosis
prevention
,
as
well
as
the
use
of
anticoagulants
to
treat
dermatologic
diseases
.
Diseases
Validation
Diseases presenting
"thrombus formation with the goal of stopping the blood loss"
symptom
sneddon syndrome
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