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Intraocular pressure control with Ahmed glaucoma drainage device in patients with cicatricial ocular surface disease-associated or aniridia-related glaucoma.
[aniridia]
To
analyze
the
control
of
intraocular
pressure
(
IOP
)
with
an
Ahmed
glaucoma
drainage
device
(
AGDD
)
in
two
groups
of
glaucoma
patients--
one
with
cicatricial
ocular
surface
disease
(
COSD
)
and
one
with
aniridia
.
This
is
a
retrospective
comparative
case
series
of
nine
patients
(
11
eyes
)
with
COSD
and
six
patients
(
8
eyes
)
with
aniridia
who
underwent
AGDD
surgery
to
control
IOP
.
The
main
outcome
measure
in
both
groups
was
stability
of
IOP
between
6
and
21
mmHg
.
Mean
IOP
decreased
significantly
in
both
groups
after
AGDD
surgery
(
29
.
6
±
8
.
7
vs
14
.
7
±
2
.
5
,
p
=
0
.
008
in
the
COSD
group
;
26
.
3
±
8
.
2
vs
15
.
3
±
5
.
8
,
p
=
0
.
008
in
the
aniridia
group
)
.
Over
a
mean
post-surgery
follow-up
of
37
.
1
months
in
the
COSD
group
,
we
managed
to
control
IOP
in
nine
eyes
;
IOP
control
was
successful
in
87
%
of
eyes
at
12
months
and
58
%
of
eyes
at
26
months
.
Over
a
mean
post-surgery
follow-up
of
37
.
4
months
in
the
aniridia
group
,
we
managed
to
control
the
IOP
in
seven
eyes
;
IOP
control
was
successful
in
87
%
of
eyes
at
12
months
.
AGDD
surgery
had
no
significant
deleterious
effect
on
visual
acuity
in
either
group
.
A
severe
complication
occurred
in
one
eye
(
1
/
8
)
in
the
aniridia
group
(
lost
vision
due
to
retinal
detachment
)
and
in
one
eye
(
1
/
11
)
in
the
COSD
group
(
tube
exposure
)
.
AGDD
surgery
is
effective
in
controlling
IOP
and
has
a
low
complication
rate
in
COSD
and
aniridia
patients
;
however
,
some
of
the
complications
are
severe
and
prompt
management
is
needed
to
prevent
deleterious
results
.
