Rare Diseases Symptoms Automatic Extraction
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A random Abstract
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Molecular confirmation of co-infection by pathogenic Leptospira spp. and Orientia tsutsugamushi in patients with acute febrile illness in Thailand.
[scrub typhus]
Leptospirosis
and
scrub
typhus
are
major
causes
of
acute
febrile
illness
in
rural
Asia
,
where
co
-infection
is
reported
to
occur
based
on
serologic
evidence
.
We
re
-examined
whether
co
-infection
occurs
by
using
a
molecular
approach
.
A
duplex
real-time
polymerase
chain
reaction
was
developed
that
targeted
a
specific
16
S
ribosomal
RNA
gene
of
pathogenic
Leptospira
spp
.
and
Orientia
tsutsugamushi
.
Of
82
patients
with
an
acute
febrile
illness
who
had
dual
infection
on
the
basis
of
serologic
tests
,
5
(
6
%
)
had
polymerase
chain
reaction
results
positive
for
both
pathogens
.
We
conclude
that
dual
infection
occurs
,
but
that
serologic
tests
may
overestimate
the
frequency
of
co
-infections
.
