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A case of Tsutsugamushi disease presenting with nephrotic syndrome.
[scrub typhus]
Nephrotic
syndrome
associated
with
Tsutsugamushi
disease
has
not
been
previously
reported
.
We
are
describing
a
case
of
Tsutsugamuchi
disease
presenting
with
nephrotic
syndrome
.
A
72
-
year
-old
woman
presented
with
fever
and
generalized
edema
.
Laboratory
studies
revealed
a
leukocytosis
,
hypoalbuminemia
,
and
hypercholesterolemia
.
Her
urine
protein
excretion
was
5
.
4
g
/
day
.
The
anti-
Tsutsugamushi
antibody
test
was
strongly
positive
(
1
:
2
,
560
)
.
A
renal
biopsy
was
performed
,
and
pathologic
findings
revealed
membranous
glomerulonephritis
.
The
patient
's
clinical
symptoms
improved
markedly
after
treatment
with
doxycycline
.