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Unusual genotypic distribution of Orientia tsutsugamushi strains causing human infections on Jeju Island.
[scrub typhus]
We
investigated
the
clinical
characteristics
and
serologic
types
of
tsutsugamushi
disease
on
the
largest
island
of
South
Korea
.
There
were
141
patients
with
tsutsugamushi
disease
at
Jeju
National
University
Hospital
and
Seogwipo
Medical
Center
between
November
of
2003
and
December
of
2012
.
Median
age
of
patients
was
61
years
,
and
59
%
were
women
.
The
major
clinical
manifestations
were
fever
(
80
.
5
%
)
and
skin
rash
(
55
.
7
%
)
,
with
eschars
evident
in
75
.
8
%
of
the
patients
.
Genotype
analysis
of
Orientia
tsutsugamushi
was
conducted
in
33
specimens
.
The
genotype
was
identified
as
Boryong
type
in
17
of
33
patients
and
Taguchi
type
in
15
of
33
patients
.
In
our
study
,
although
the
Taguchi
genotype
is
rarely
reported
in
the
endemic
area
,
it
was
common
on
Jeju
Island
.
This
genotype
may
be
associated
with
mild
and
moderate
forms
of
tsutsugamushi
disease
.
