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[Clinical characteristics of 32 cases of tsutsugamushi disease in Suqian Municipality].
[scrub typhus]
To
understand
the
clinical
characteristics
of
tsutsugamushi
disease
in
Suqian
Municipality
,
Jiangsu
Province
so
as
to
guide
the
diagnosis
and
treatment
of
this
disease
.
The
clinical
data
of
32
patients
diagnosed
as
tsutsugamushi
disease
in
our
hospital
during
the
past
2
years
were
analyzed
retrospectively
.
Tsutsugamushi
disease
occurred
frequently
between
August
and
December
.
All
the
32
patients
had
the
history
of
contacting
grass
and
brushwood
,
and
all
of
them
showed
the
signs
of
pyrexia
,
eschar
,
ulcer
,
swelling
of
lymph
nodes
and
rash
.
Liver
damages
were
observed
in
30
cases
(
93
.
75
%
)
.
Pulmonary
imaging
changes
were
observed
in
14
cases
(
43
.
75
%
)
.
Heart
damages
were
noticed
in
9
cases
(
28
.
13
%
)
.
Kidney
damages
were
noticed
in
6
cases
(
18
.
75
%
)
.
One
case
was
complicated
by
multiple
organ
dysfunction
syndromes
(
MODS
)
and
disseminated
intravascular
coagulation
(
DIC
)
.
The
OX
19
and
OX
2
antigen
agglutination
reaction
of
bacillus
proteus
were
negative
in
all
the
cases
.
The
OXK
antigen
agglutination
reaction
of
bacillus
proteus
was
positive
in
6
cases
(
18
.
75
%
)
.
Among
32
cases
,
24
cases
were
misdiagnosed
in
the
first
visiting
clinic
.
The
misdiagnosis
rate
of
the
initial
diagnosis
of
this
disease
reached
as
high
as
75
%
.
Azithromycin
was
effective
.
The
curative
rate
was
96
.
88
%
and
the
mortality
was
3
.
13
%
(
1
case
)
.
Clinical
characteristics
of
tsutsugamushi
disease
are
complicated
,
and
it
is
commonly
complicated
with
liver
damages
.
The
Weil-
Felix
test
is
not
very
important
to
initial
diagnosis
for
tsutsugamushi
disease
in
local
.
For
patients
as
fever
with
unknown
origin
(
FUO
)
and
with
the
liver
damage
,
the
diagnosis
of
tsutsugamushi
disease
should
be
reminded
.
Diseases
Validation
Diseases presenting
"fever"
symptom
22q11.2 deletion syndrome
acute rheumatic fever
alexander disease
allergic bronchopulmonary aspergillosis
canavan disease
carcinoma of the gallbladder
child syndrome
congenital toxoplasmosis
cushing syndrome
cystinuria
dracunculiasis
erdheim-chester disease
esophageal adenocarcinoma
esophageal carcinoma
familial mediterranean fever
focal myositis
hodgkin lymphoma, classical
lamellar ichthyosis
legionellosis
locked-in syndrome
malignant atrophic papulosis
neonatal adrenoleukodystrophy
neuralgic amyotrophy
oculocutaneous albinism
papillon-lefèvre syndrome
pyomyositis
pyruvate dehydrogenase deficiency
scrub typhus
severe combined immunodeficiency
sneddon syndrome
systemic capillary leak syndrome
triple a syndrome
typhoid
waldenström macroglobulinemia
wolf-hirschhorn syndrome
This symptom has already been validated
