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A random Abstract
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A case series of possibly recrudescent Orientia tsutsugamushi infection presenting as pneumonia.
[scrub typhus]
Orientia
tsutsugamushi
remains
latent
in
humans
after
scrub
typhus
.
Pneumonia
occurs
as
a
complication
of
scrub
typhus
in
the
late
-phase
disease
.
However
,
pneumonia
may
also
occur
as
a
presenting
manifestation
of
O
.
tsutsugamushi
infection
.
We
reviewed
the
cases
of
3
patients
with
atypical
pneumonia
who
presented
at
our
hospital
and
were
later
confirmed
to
have
O
.
tsutsugamushi
infection
by
serology
,
nested
polymerase
chain
reaction
(
PCR
)
,
and
cell
culture
.
All
patients
were
young
adults
with
no
history
of
scrub
typhus
,
and
none
claimed
to
have
recently
been
exposed
to
areas
where
scrub
typhus
is
endemic
.
Two
cases
occurred
in
non-outbreak
seasons
.
Furthermore
,
eschar
was
not
observed
.
Pneumonia
was
documented
within
4
days
after
fever
onset
.
The
immunoglobulin
(
Ig
)
G
antibody
titers
against
O
.
tsutsugamushi
were
higher
than
the
IgM
titers
,
although
the
serologic
test
results
were
less
helpful
in
the
diagnosis
.
Nested
PCR
and
cell
culture
of
blood
specimens
confirmed
the
diagnosis
of
O
.
tsutsugamushi
infection
.
These
findings
suggest
that
pneumonia
can
occur
as
a
result
of
recrudescence
of
latent
O
.
tsutsugamushi
infection
.
Diseases
Validation
Diseases presenting
"pneumonia"
symptom
22q11.2 deletion syndrome
acute rheumatic fever
allergic bronchopulmonary aspergillosis
alpha-thalassemia
classical phenylketonuria
cohen syndrome
congenital diaphragmatic hernia
heparin-induced thrombocytopenia
hydrocephalus with stenosis of the aqueduct of sylvius
junctional epidermolysis bullosa
lamellar ichthyosis
legionellosis
liposarcoma
lymphangioleiomyomatosis
monosomy 21
oculocutaneous albinism
omenn syndrome
pleomorphic liposarcoma
primary effusion lymphoma
proteus syndrome
pyomyositis
scrub typhus
severe combined immunodeficiency
triple a syndrome
waldenström macroglobulinemia
wiskott-aldrich syndrome
x-linked adrenoleukodystrophy
zellweger syndrome
This symptom has already been validated
