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Continuous pH monitoring using the Paratrend 7 inserted into a peripheral vein in a patient with shock and congenital lactic acidosis.
[pyruvate dehydrogenase deficiency]
The
authors
present
a
25
-
year
-old
woman
who
was
admitted
to
the
ICU
for
treatment
of
shock
,
respiratory
failure
,
and
acidosis
related
to
congenital
lactic
acidosis
from
pyruvate
dehydrogenase
deficiency
.
To
aid
in
ongoing
management
of
the
metabolic
acidosis
,
the
Paratrend
blood
gas
monitoring
sensor
was
inserted
through
a
peripheral
venous
site
to
provide
a
continuous
measurement
of
pH
and
partial
pressure
of
carbon
dioxide
(
Pco
2
)
.
With
the
venous
insertion
of
the
Paratrend
,
a
clinically
useful
correlation
with
arterial
blood
gas
values
was
noted
.
Linear
regression
analysis
of
the
pH
values
from
the
venous
blood
gas
analyses
and
the
Paratrend
monitor
revealed
r
2
=
0
.
71
with
p
=
0
.
001
and
r
2
=
0
.
78
with
a
p
=
0
.
0003
for
the
Pco
2
values
.
Our
preliminary
experience
suggests
that
venous
placement
of
the
Paratrend
monitor
can
be
used
to
provide
clinically
useful
,
continuous
measurement
of
pH
and
Pco
2
.
Diseases
Validation
Diseases presenting
"and acidosis related to congenital lactic acidosis from pyruvate dehydrogenase deficiency"
symptom
pyruvate dehydrogenase deficiency
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