Continuous pH monitoring using the Paratrend 7 inserted into a peripheral vein in a patient with shock and congenital lactic acidosis.

[pyruvate dehydrogenase deficiency]

The authors present a 25 -year -old woman who was admitted to the ICU for treatment of shock , respiratory failure , and acidosis related to congenital lactic acidosis from pyruvate dehydrogenase deficiency . To aid in ongoing management of the metabolic acidosis , the Paratrend blood gas monitoring sensor was inserted through a peripheral venous site to provide a continuous measurement of pH and partial pressure of carbon dioxide (Pco 2 ). With the venous insertion of the Paratrend , a clinically useful correlation with arterial blood gas values was noted . Linear regression analysis of the pH values from the venous blood gas analyses and the Paratrend monitor revealed r 2 = 0 .71 with p = 0 .001 and r 2 = 0 .78 with a p = 0 .0003 for the Pco 2 values . Our preliminary experience suggests that venous placement of the Paratrend monitor can be used to provide clinically useful , continuous measurement of pH and Pco 2 .

Diseases
Validation

Diseases presenting "venous placement" symptom

pyruvate dehydrogenase deficiency

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