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Continuous pH monitoring using the Paratrend 7 inserted into a peripheral vein in a patient with shock and congenital lactic acidosis.
[pyruvate dehydrogenase deficiency]
The
authors
present
a
25
-
year
-old
woman
who
was
admitted
to
the
ICU
for
treatment
of
shock
,
respiratory
failure
,
and
acidosis
related
to
congenital
lactic
acidosis
from
pyruvate
dehydrogenase
deficiency
.
To
aid
in
ongoing
management
of
the
metabolic
acidosis
,
the
Paratrend
blood
gas
monitoring
sensor
was
inserted
through
a
peripheral
venous
site
to
provide
a
continuous
measurement
of
pH
and
partial
pressure
of
carbon
dioxide
(
Pco
2
)
.
With
the
venous
insertion
of
the
Paratrend
,
a
clinically
useful
correlation
with
arterial
blood
gas
values
was
noted
.
Linear
regression
analysis
of
the
pH
values
from
the
venous
blood
gas
analyses
and
the
Paratrend
monitor
revealed
r
2
=
0
.
71
with
p
=
0
.
001
and
r
2
=
0
.
78
with
a
p
=
0
.
0003
for
the
Pco
2
values
.
Our
preliminary
experience
suggests
that
venous
placement
of
the
Paratrend
monitor
can
be
used
to
provide
clinically
useful
,
continuous
measurement
of
pH
and
Pco
2
.
Diseases
Validation
Diseases presenting
"metabolic acidosis"
symptom
congenital diaphragmatic hernia
homocystinuria without methylmalonic aciduria
neonatal adrenoleukodystrophy
pendred syndrome
pyruvate dehydrogenase deficiency
scrub typhus
systemic capillary leak syndrome
This symptom has already been validated
