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A random Abstract
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Spectrum of congenital defects of the eye and its adnexia in the pediatric age group; experience at a tertiary facility in Nigeria.
[aniridia]
The
aim
of
this
study
was
to
investigate
the
types
and
presentation
pattern
of
congenital
defects
of
the
eye
and
adnexia
in
our
center
.
This
is
a
retrospective
review
of
congenital
defects
of
the
eye
and
adnexia
over
a
20
-
month
period
at
a
tertiary
referral
center
in
Lagos
,
Nigeria
.
Records
were
analyzed
for
age
at
presentation
,
laterality
,
gender
,
vision
assessment
,
and
type
(
s
)
of
abnormality
.
Out
of
412
pediatric
patients
,
40
(
9
.
7
Â
%
)
were
seen
to
have
congenital
abnormality
of
the
eye
and
/
or
its
adnexia
during
the
study
period
.
There
were
17
(
42
.
5
Â
%
)
males
.
Twelve
patients
(
30
.
0
Â
%
)
presented
with
involvement
of
the
right
eyes
,
nine
(
22
.
5
Â
%
)
with
left
eyes
,
while
19
(
47
.
5
Â
%
)
had
bilateral
involvement
.
Twenty
-
eight
patients
(
70
.
0
Â
%
)
were
aged
1
Â
year
or
less
at
the
time
of
presentation
.
A
total
of
69
entities
were
recognized
as
some
children
had
two
or
more
malformations
.
The
common
congenital
defects
identified
were
cataract
(
39
.
1
Â
%
)
,
ptosis
(
17
.
4
Â
%
)
,
glaucoma
(
8
.
7
Â
%
)
,
and
cornea
opacity
(
7
.
2
Â
%
)
.
Other
less
common
congenital
defects
include
:
microphthalmos
,
anophthalmos
,
coloboma
(
lid
and
iris
)
,
dermoid
cyst
,
and
aniridia
.
All
of
the
patients
with
available
visual
acuity
documentation
had
visual
impairment
.
A
high
proportion
of
the
patients
were
lost
to
follow-up
.
Cataract
,
ptosis
,
and
glaucoma
were
the
commonest
congenital
defects
of
the
eye
and
adnexia
in
our
center
and
were
associated
with
visual
impairments
.
The
significant
loss
of
the
patients
during
follow-up
needs
urgent
investigation
and
attention
to
forestall
this
trend
.
Diseases
Validation
Diseases presenting
"glaucoma"
symptom
22q11.2 deletion syndrome
aniridia
coats disease
cohen syndrome
krabbe disease
oculocutaneous albinism
oligodontia
proteus syndrome
wiskott-aldrich syndrome
wolf-hirschhorn syndrome
This symptom has already been validated
