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Recent lessons for the management of bone and joint infections.
[pyomyositis]
The
epidemiology
and
clinical
manifestations
of
osteoarticular
infections
are
changing
primarily
as
a
result
of
the
emergence
of
community-acquired
methicillin-resistant
Staphylococcus
aureus
infections
.
Multifocal
disease
,
venous
thrombosis
and
pathologic
fractures
are
manifestations
of
CA
-MRSA
osteomyelitis
.
MRI
is
the
diagnostic
imaging
modality
of
choice
for
musculoskeletal
infections
.
Nafcillin
/
oxacillin
or
cefazolin
remains
the
antibiotic
of
choice
for
treating
infections
caused
by
MSSA
.
A
β-lactam
antibiotic
is
recommended
for
Kingella
kingae
.
Vancomycin
and
clindamycin
are
the
first
line
agents
for
treating
osteomyelitis
caused
by
CA
-MRSA
.
A
short
course
of
parenteral
antibiotics
followed
by
appropriate
oral
antibiotics
is
equivalent
to
total
course
of
parenteral
antibiotics
for
most
patients
and
avoids
the
risks
associated
with
PICCs
.
Surgical
drainage
of
subperiosteal
abscesses
and
surrounding
pyomyositis
is
common
with
S
.
aureus
clones
currently
circulating
.
Collaboration
with
hematologists
for
managing
patients
with
venous
thromboses
is
recommended
.
Diseases
Validation
Diseases presenting
"mssa"
symptom
pyomyositis
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