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Musculoskeletal and rheumatological disorders in HIV infection: Experience in a tertiary referral center.
[pyomyositis]
Musculoskeletal
involvement
in
human
immunodeficiency
virus
(
HIV
)
infected
patients
are
important
disease
manifestations
,
responsible
for
increased
morbidity
and
also
decreased
quality
of
life
.
To
study
the
spectrum
of
different
musculoskeletal
involvement
in
HIV
infected
patients
and
its
impact
on
quality
of
life
.
Three
hundred
(
n
=
300
)
HIV-
1
reactive
patients
were
evaluated
in
respect
to
different
musculoskeletal
involvement
including
the
quality
of
life
from
January
2010
to
January
2011
.
Male
to
female
ratio
was
11
:
1
with
a
mean
age
of
35
(
±
6
.
4
)
years
and
mean
duration
of
the
disease
was
3
(
±
1
.
54
)
years
.
Majority
of
cases
were
truck
drivers
,
motel
workers
,
and
jewelry
workers
.
Musculoskeletal
disorders
were
observed
in
a
total
of
190
cases
(
63
.
33
%
)
.
The
spectrum
of
musculoskeletal
involvement
was
:
Body
ache
in
140
(
46
.
7
%
)
,
arthralgia
in
80
(
26
.
7
%
)
,
mechanical
low
back
pain
in
25
(
8
.
3
%
)
,
osteoporosis
in
20
(
6
.
7
%
)
,
painful
articular
syndrome
in
10
(
3
.
3
%
)
,
hypertrophic
osteoarthropathy
in
two
(
0
.
7
%
)
,
pyomyositis
in
two
(
0
.
7
%
)
,
osteomyelitis
in
one
(
0
.
3
%
)
,
and
avascular
bone
necrosis
in
one
patient
(
0
.
3
%
)
.
Rheumatologic
disorders
associated
were
:
Reactive
arthritis
in
seven
(
2
.
3
%
)
,
fibromyalgia
in
four
(
1
.
3
%
)
,
septic
arthritis
in
three
(
1
%
)
,
acute
gout
in
three
(
1
%
)
,
spondyloarthropathy
in
two
(
0
.
7
%
)
,
rheumatoid
arthritis
in
two
(
0
.
7
%
)
,
dermatomyositis
in
one
(
0
.
3
%
)
,
and
systemic
lupus
erythematosus
(
SLE
)
in
one
patient
(
0
.
3
%
)
.
But
HIV
associated
arthritis
and
diffuse
infiltrative
lymphocytosis
syndrome
(
DILS
)
were
not
detected
.
Most
of
the
patients
had
decreased
quality
of
life
.
Musculoskeletal
involvement
was
common
in
HIV
patients
causing
increased
morbidity
,
so
early
detection
and
timely
intervention
is
essential
to
improve
quality
of
life
.
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pyomyositis
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