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Musculoskeletal and rheumatological disorders in HIV infection: Experience in a tertiary referral center.
[pyomyositis]
Musculoskeletal
involvement
in
human
immunodeficiency
virus
(
HIV
)
infected
patients
are
important
disease
manifestations
,
responsible
for
increased
morbidity
and
also
decreased
quality
of
life
.
To
study
the
spectrum
of
different
musculoskeletal
involvement
in
HIV
infected
patients
and
its
impact
on
quality
of
life
.
Three
hundred
(
n
=
300
)
HIV-
1
reactive
patients
were
evaluated
in
respect
to
different
musculoskeletal
involvement
including
the
quality
of
life
from
January
2010
to
January
2011
.
Male
to
female
ratio
was
11
:
1
with
a
mean
age
of
35
(
±
6
.
4
)
years
and
mean
duration
of
the
disease
was
3
(
±
1
.
54
)
years
.
Majority
of
cases
were
truck
drivers
,
motel
workers
,
and
jewelry
workers
.
Musculoskeletal
disorders
were
observed
in
a
total
of
190
cases
(
63
.
33
%
)
.
The
spectrum
of
musculoskeletal
involvement
was
:
Body
ache
in
140
(
46
.
7
%
)
,
arthralgia
in
80
(
26
.
7
%
)
,
mechanical
low
back
pain
in
25
(
8
.
3
%
)
,
osteoporosis
in
20
(
6
.
7
%
)
,
painful
articular
syndrome
in
10
(
3
.
3
%
)
,
hypertrophic
osteoarthropathy
in
two
(
0
.
7
%
)
,
pyomyositis
in
two
(
0
.
7
%
)
,
osteomyelitis
in
one
(
0
.
3
%
)
,
and
avascular
bone
necrosis
in
one
patient
(
0
.
3
%
)
.
Rheumatologic
disorders
associated
were
:
Reactive
arthritis
in
seven
(
2
.
3
%
)
,
fibromyalgia
in
four
(
1
.
3
%
)
,
septic
arthritis
in
three
(
1
%
)
,
acute
gout
in
three
(
1
%
)
,
spondyloarthropathy
in
two
(
0
.
7
%
)
,
rheumatoid
arthritis
in
two
(
0
.
7
%
)
,
dermatomyositis
in
one
(
0
.
3
%
)
,
and
systemic
lupus
erythematosus
(
SLE
)
in
one
patient
(
0
.
3
%
)
.
But
HIV
associated
arthritis
and
diffuse
infiltrative
lymphocytosis
syndrome
(
DILS
)
were
not
detected
.
Most
of
the
patients
had
decreased
quality
of
life
.
Musculoskeletal
involvement
was
common
in
HIV
patients
causing
increased
morbidity
,
so
early
detection
and
timely
intervention
is
essential
to
improve
quality
of
life
.
Diseases
Validation
Diseases presenting
"osteoporosis"
symptom
achondroplasia
adrenal incidentaloma
allergic bronchopulmonary aspergillosis
aromatase deficiency
congenital adrenal hyperplasia
cushing syndrome
cutaneous mastocytosis
dentinogenesis imperfecta
erythropoietic protoporphyria
fabry disease
familial hypocalciuric hypercalcemia
familial mediterranean fever
inclusion body myositis
kallmann syndrome
oligodontia
pyomyositis
werner syndrome
x-linked adrenoleukodystrophy
This symptom has already been validated
