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Overgrowth conditions: a diagnostic and therapeutic conundrum.
[proteus syndrome]
Over
the
past
five
decades
,
one
of
the
major
problems
in
the
treatment
of
overgrowth
syndromes
of
the
hand
has
been
classification
.
Currently
,
a
number
of
specific
conditions
with
known
natural
histories
have
been
delineated
and
reviewed
.
Treatment
is
highly
individualized
.
Amputation
is
still
recommended
for
grotesque
deformities
of
the
upper
limb
.
Early
aggressive
surgery
,
when
indicated
,
will
improve
contour
,
function
,
and
appearance
.
Specific
therapeutic
techniques
include
radical
debulking
,
microvascular
neurolysis
,
vascular
reconstruction
,
epiphysiodesis
,
and
,
in
some
cases
,
thumb
or
digit
replacement
.
Long
-term
outcomes
remain
in
the
good-
to
-fair
range
and
are
dependent
upon
the
condition
,
reconstructive
techniques
employed
,
age
of
patient
,
and
the
severity
of
deformity
.
Diseases
Validation
Diseases presenting
"specific conditions"
symptom
proteus syndrome
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