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Proteus syndrome: three case reports with a review of the literature.
[proteus syndrome]
Proteus
syndrome
(
PS
)
is
a
rare
,
progressive
disorder
that
manifests
as
asymmetric
,
disproportionate
overgrowth
affecting
tissues
derived
from
any
germline
layer
.
Cases
of
PS
from
2005
-
2010
were
retrieved
from
the
pathology
files
at
our
institution
.
Two
confirmed
cases
and
one
possible
case
of
PS
were
identified
.
All
patients
came
from
different
ethnic
backgrounds
.
Patient
1
displayed
classic
skin
and
overgrowth
lesions
.
Patient
2
displayed
various
features
,
particularly
vascular
malformations
.
Patient
3
demonstrated
a
cerebriform
connective
tissue
nevus
alone
.
These
patients
demonstrate
the
spectrum
of
presentations
of
PS
.
Much
is
left
to
learn
about
this
disfiguring
disease
.
Diseases
Validation
Diseases presenting
"displayed classic skin and overgrowth lesions"
symptom
proteus syndrome
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