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Heart failure with mitral valve regurgitation due to primary hyperoxaluria type 1: case report with review of the literature.
[primary hyperoxaluria type 1]
Primary
hyperoxaluria
type
I
(
PH
I
)
is
a
rare
recessive
autosomal
disorder
characterized
by
systemic
calcium
oxalate
depositions
,
that
results
in
renal
failure
and
systemic
oxalosis
.
We
report
a
38
-
year
-old
male
with
cardiac
oxalosis
,
a
severe
complication
of
PHI
,
presenting
with
an
infiltrative
cardiomyopathy
,
secondary
heart
failure
and
severe
mitral
regurgitation
,
necessitating
surgical
repair
to
allow
combined
liver
-kidney
transplantation
.
We
discuss
pathogenesis
,
diagnostics
and
therapy
of
this
clinical
entity
by
reviewing
literature
.
Diseases
Validation
Diseases presenting
"liver-kidney transplantation"
symptom
primary hyperoxaluria type 1
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