Conservative treatment of a pathological fracture in a 3-year-old boy with primary hyperoxaluria type I.

[primary hyperoxaluria type 1]

Primary hyperoxaluria type I is a rare inherited disease that presents a disturbed metabolism of glyoxylate . Consequently , patients suffer from hyperoxaluria , leading to renal failure and subsequent skeletal calcium oxalate deposition . Areas with high concentrations of calcium oxalate , so -called dense metaphyseal bands , are at risk for pathological fracturing . The primary disease is treated by combined liver -kidney transplantation , although pathological fracturing also occurs in the posttransplant period . In the current case , we present a 3 -year -old boy with a pathological fracture of his right femur , 2 years after liver -kidney transplantation . We opted for a conservative regime , leading to good fracture healing . As there are limited data in the literature regarding treatment of fractures in these patients , it is important to notify the outcome of conservative treatment of pathological fractures in patients with primary hyperoxaluria type I .