Human Immunodeficiency Virus (HIV)-Negative and Human Herpes Virus-8 (HHV-8)-Positive Primary Effusion Lymphoma: A Case Report and Review of the Literature.

[primary effusion lymphoma]

Primary effusion lymphoma (PEL ) is a rare type of non-Hodgkin lymphoma that presents with serosal effusion in body cavities , without obvious tumor masses . Although PEL occurs in immunocompromised patients that are human immunodeficiency virus (HIV ) positive , it also occurs in immunocompetent human herpes virus-8 (HHV-8 )-positive patients . Herein we present an immunocompetent , HIV-negative , CD-20 -negative , HHV-8 -positive patient with pleural effusion that was diagnosed as PEL . The CHOP protocol and talc pleurodesis were administered . HHV-8 plays a causative role in PEL and is important for differentiating PEL from other types of lymphoma . As such , in addition to pleurodesis antiviral treatment should be considered for optimal treatment outcome .None declared .

Diseases
Validation

Diseases presenting "positive patients" symptom

allergic bronchopulmonary aspergillosis

cadasil

cholangiocarcinoma

cowden syndrome

esophageal squamous cell carcinoma

heparin-induced thrombocytopenia

hodgkin lymphoma, classical

kabuki syndrome

kallmann syndrome

primary effusion lymphoma

sneddon syndrome

typhoid

waldenstrÃ¶m macroglobulinemia

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