Human Immunodeficiency Virus (HIV)-Negative and Human Herpes Virus-8 (HHV-8)-Positive Primary Effusion Lymphoma: A Case Report and Review of the Literature.

[primary effusion lymphoma]

Primary effusion lymphoma (PEL ) is a rare type of non-Hodgkin lymphoma that presents with serosal effusion in body cavities , without obvious tumor masses . Although PEL occurs in immunocompromised patients that are human immunodeficiency virus (HIV ) positive , it also occurs in immunocompetent human herpes virus-8 (HHV-8 )-positive patients . Herein we present an immunocompetent , HIV-negative , CD-20 -negative , HHV-8 -positive patient with pleural effusion that was diagnosed as PEL . The CHOP protocol and talc pleurodesis were administered . HHV-8 plays a causative role in PEL and is important for differentiating PEL from other types of lymphoma . As such , in addition to pleurodesis antiviral treatment should be considered for optimal treatment outcome .None declared .

Diseases
Validation

Diseases presenting "pleural effusion" symptom

allergic bronchopulmonary aspergillosis

cushing syndrome

dedifferentiated liposarcoma

erdheim-chester disease

esophageal carcinoma

hydrocephalus with stenosis of the aqueduct of sylvius

lymphangioleiomyomatosis

pleomorphic liposarcoma

primary effusion lymphoma

scrub typhus

systemic capillary leak syndrome

thoracic outlet syndrome

waldenstrÃ¶m macroglobulinemia

wolf-hirschhorn syndrome

This symptom has already been validated