[A case of liposarcoma of the sigmoid colon mesenterium successfully treated with chemotherapy].

[pleomorphic liposarcoma]

We report a case of postoperative recurrence of liposarcoma of the mesenterium successfully treated by chemotherapy using ifosfamide (IFM ) and cisplatin (CDDP ). A 58 -year -old man presented with a strange feeling in the lower abdomen . Enhanced computed tomography showed enhanced non-epithelial tumor in the pelvic space . The tumor moved on palpation , so we diagnosed liposarcoma from the mesenterium , and resected the tumor on 22 August , 2002 . The pleomorphic liposarcoma was 11 x 14 x 7 cm , growing from the mesenterium of the sigmoid colon , and weighed 640 g . We performed re -operation due to pelvic recurrence on 24 March , 2003 . On 18 September of the same year , when we performed re -operation again for pelvic recurrence , there were so many recurrences on the mesenterium of small intestine that resection was impossible . We started chemotherapy 3 days later using 3 .0 g /body IFM from 1 October 2003 , together with 1 ,800 mg /body mesna for prevention of hemorrhage cystitis . We continued chemotherapy using 3 .0 g /body /day IFM together with 1 , 800 mg /body /day mesna on an outpatient basis , upon his weekly visit to the hospital . Patient remission was shown by abdominal enhanced computed tomography on 10 December . Some grade 2 alopecia and grade 2 leukopenia occurred , so we changed to chemotherapy once every two weeks . Then , it continued to decrease , without any side effects . The response appeared to be complete on computed tomography in August 2004 , and we have been continuing the same chemotherapy without recurrence .

Diseases
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Diseases presenting "grade 2 leukopenia occurred" symptom

pleomorphic liposarcoma

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