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Mediastinal pleomorphic liposarcoma diagnosed by fine needle aspiration biopsy: a case report.
[pleomorphic liposarcoma]
Progress
in
radiology
and
pathology
for
diagnosing
mediastinal
tumors
has
R
been
made
in
recent
decades
,
thanks
to
the
use
of
fine
needle
aspiration
biopsy
(
FNAB
)
guided
by
computed
tomography
,
which
has
replaced
mediastinoscopy
and
open
biopsies
.
A
66
-
year
-old
male
had
a
history
o
productive
coughing
with
mucopurulent
expectoration
,
progressive
dyspnea
,
arthralgias
,
myalgias
,
astenia
and
adynamia
for
the
previous
3
months
.
A
CT
scan
and
magnetic
resonance
imaging
revealed
a
poorly
limited
tumor
mass
ofheterogeneous
den
sity
in
the
anterior
mediastinum
.
FNAB
of
the
tumor
mass
showed
malignant
cells
compatible
with
liposarcoma
.
CONCLUSLON
:
Of
the
several
types
of
mesenchymal
mediastinal
neoplasms
,
liposarcoma
is
the
most
important
.
Many
of
them
are
seen
in
adults
,
and
<
10
cases
have
been
diagnosed
in
children
.
The
symptoms
are
related
to
compression
of
the
nearby
airways
.
Usually
liposarcomas
are
yellow
,
lobed
tumors
without
capsules
that
infiltrate
adjacent
organs
and
tissues
.
Microscopically
,
they
have
the
same
histologic
spectrum
as
tumors
originating
in
other
sites
.
Thus
,
it
is
common
to
observe
all
the
histologic
varieties
of
soft
tissue
liposarcomas
.
The
identification
of
lipoblasts
is
the
key
to
the
correct
diagnosis
in
FNAB
material
.
Diseases
Validation
Diseases presenting
"open biopsies"
symptom
pleomorphic liposarcoma
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