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Epithelioid variant of pleomorphic liposarcoma in a heifer.
[pleomorphic liposarcoma]
A
case
of
epithelioid
variant
of
liposarcoma
in
a
31
-
month
-old
Japanese
Black
heifer
is
described
.
The
tumour
mass
,
which
formed
in
the
subcutis
of
the
left
cheek
,
was
excised
surgically
,
but
this
was
followed
by
recurrence
and
metastasis
to
lymph
nodes
.
The
primary
tumour
was
composed
of
sheets
of
lipid-laden
cells
,
and
anaplastic
larger
cells
with
eosinophilic
or
amphophilic
cytoplasm
were
occasionally
seen
.
In
addition
to
vimentin
and
S-
100
protein
expression
in
the
majority
of
tumour
cells
,
squamous
and
non-squamous
cytokeratins
(
CKs
)
were
present
,
mainly
in
the
larger
cells
,
which
predominated
in
the
metastatic
lesions
.
The
expression
of
CKs
was
considered
to
be
evidence
of
epithelioid
differentiation
.
