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[A case of pleomorphic liposarcoma in a patient with Crohn's disease taking azathioprine].
[pleomorphic liposarcoma]
Azathioprine
is
frequently
used
for
the
treatment
of
inflammatory
bowel
diseases
(
IBD
)
such
as
Crohn
's
disease
and
ulcerative
colitis
.
Lymphomas
,
squamous
cell
carcinomas
,
and
undifferentiated
pleomorphic
sarcomas
have
been
reported
among
patients
receiving
azathioprine
therapy
.
Herein
,
we
report
a
case
of
pleomorphic
liposarcoma
of
chest
wall
which
occurred
in
a
44
-
year
-old
man
with
Crohn
's
disease
taking
azathioprine
.
He
was
diagnosed
with
Crohn
's
disease
3
years
ago
after
suffering
from
abdominal
pain
and
hematochezia
for
12
years
.
He
had
been
taking
50
mg
of
azathioprine
per
day
for
23
months
when
he
visited
the
thoracic
and
cardiovascular
surgery
clinic
due
to
right
chest
palpable
mass
that
had
rapidly
grown
during
the
past
2
months
.
Excisional
biopsy
was
performed
and
the
mass
was
diagnosed
as
pleomorphic
liposarcoma
.
Therefore
,
he
underwent
radical
excision
of
the
right
chest
wall
mass
,
which
measured
11
.
0
×
6
.
5
cm
in
size
.
He
is
scheduled
to
receive
radiation
therapy
and
chemotherapy
.