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Challenging epithelioid mesenchymal neoplasms: mimics and traps.
[pleomorphic liposarcoma]
Epithelioid
mesenchymal
malignancies
represent
a
major
diagnostic
challenge
.
Epithelioid
morphology
can
be
observed
in
a
variety
of
soft
tissue
neoplasms
,
however
there
exist
specific
subtypes
in
which
an
epithelioid
apperance
constitutes
the
most
distinctive
morphological
feature
.
Moving
from
epithelioid
sarcoma
of
Enzinger
(
the
prototype
of
sarcoma
with
epithelioid
morphology
)
,
this
review
will
focus
on
the
most
relevant
entities
:
namely
epithelioid
haemangioendothelioma
and
angiosarcoma
,
pseudomyogenic
haemangioendothelioma
,
epithelioid
malignant
peripheral
nerve
sheath
tumour
,
epithelioid
sclerosing
fibrosarcoma
,
epithelioid
pleomorphic
liposarcoma
,
alveolar
soft
part
sarcoma
,
and
undifferentiated
soft
tissue
sarcoma
with
epithelioid
morphology
.
Differential
diagnoses
and
major
pitfalls
will
be
discussed
in
detail
.
Diseases
Validation
Diseases presenting
"soft tissue neoplasms"
symptom
dedifferentiated liposarcoma
liposarcoma
pleomorphic liposarcoma
well-differentiated liposarcoma
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