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Breastfeeding infants with phenylketonuria in the United States and Canada.
[phenylketonuria]
This
study
described
the
prevalence
and
duration
of
mothers
'
breastfeeding
infants
with
phenylketonuria
(
PKU
)
and
explored
factors
related
to
duration
of
breastfeeding
as
a
surrogate
for
breastfeeding
success
.
Descriptive
analysis
as
performed
from
an
international
Internet
survey
of
mothers
(
n
=
103
)
who
met
the
inclusion
criteria
:
(
1
)
at
least
21
years
of
age
,
(
2
)
able
to
read
and
write
in
English
,
(
3
)
child
with
PKU
,
and
(
4
)
living
in
the
United
States
or
Canada
.
Of
the
103
mothers
,
89
(
86
%
)
initiated
breastfeeding
immediately
following
delivery
,
whereas
14
(
14
%
)
chose
bottle
feeding
.
In
comparison
to
breastfeeding
after
delivery
,
significantly
fewer
mothers
breastfed
after
diagnosis
(
McNemar
's
χ
(
2
)
=
30
.
33
,
p
<
0
.
001
;
n
=
72
vs
.
n
=
89
)
.
Breastfeeding
duration
ranged
from
less
than
1
month
to
24
months
with
one
modal
duration
category
(
n
=
20
,
22
%
)
at
less
than
1
month
.
The
timing
of
the
addition
of
commercial
infant
formula
to
supplement
breastfeeding
or
expressed
mothers
'
milk
was
associated
with
a
shorter
duration
of
breastfeeding
among
infants
with
PKU
:
χ
(
2
)
(
42
,
n
=
73
)
=
88
.
13
,
p
<
0
.
001
.
PKU
is
treated
with
phenylalanine
(
Phe
)
restriction
.
Breastfeeding
infants
with
PKU
is
challenging
in
part
because
Phe
intake
is
difficult
to
determine
precisely
.
We
studied
breastfeeding
duration
in
infants
with
PKU
and
factors
associated
with
success
.
Further
research
should
identify
the
unique
needs
of
mothers
'
breastfeeding
infants
with
PKU
to
guide
the
development
of
interventions
specific
to
these
mothers
to
support
their
efforts
to
continue
breastfeeding
after
the
diagnosis
of
PKU
.
Diseases
Validation
Diseases presenting
"success"
symptom
phenylketonuria
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