Live birth following double-factor pre-implantation genetic diagnosis for both reciprocal translocation and alpha-thalassaemia.

[alpha-thalassemia]

We report a live birth from a couple with two genetic diseases , namely : reciprocal translocation carrier and alpha-thalassaemia trait , following pre-implantation genetic diagnostic tests . This is the first case in Hong Kong in which the technique of using one blastomere biopsy for two diseases was established , using array comparative genomic hybridisation and polymerase chain reaction .