Aggressive periodontitis associated with Papillon-LefÃ¨vre syndrome: report of a 14-year follow-up.

[papillon-lefÃ¨vre syndrome]

This case report describes the periodontal management , therapeutic approach , and 14 -year follow-up of a patient diagnosed with Papillon-Lefevre syndrome (PLS ). A female child , diagnosed with PLS -associated periodontitis at the age of 9 years and 11 months , presented with hyperkeratosis of the palms and soles , as well as generalized aggressive periodontitis . The dental treatment comprised standard periodontal debridement , scaling and root planing , instructions on oral hygiene , restorations , extraction of hopelessly affected teeth and a therapeutic use of antibiotics . The concomitant supportive periodontal therapy and antibiotic coverage could not stop the loss of periodontal attachment and destruction of the alveolar bone . Four years after treatment was initiated , the last remaining teeth were extracted and complete dentures were constructed . The dentures have been periodically replaced and the patient continues to return for follow-up once a year . The combination of intensive periodontal treatment and antibiotic regimen only temporarily delayed periodontal disease progression and did not prevent loss of both primary and permanent teeth . The outcome of this long -term follow-up case report shows that management of PLS -associated periodontitis is further complicated when the patient is first seen in the mixed dentition stage or later . In these situations , the chances of controlling the progression of periodontal breakdown and minimizing tooth loss are greatly reduced .

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Diseases presenting "antibiotic regimen only temporarily delayed periodontal disease progression and did not prevent loss of both primary and permanent teeth" symptom

papillon-lefÃ¨vre syndrome

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