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Aggressive periodontitis associated with Papillon-Lefèvre syndrome: report of a 14-year follow-up.
[papillon-lefèvre syndrome]
This
case
report
describes
the
periodontal
management
,
therapeutic
approach
,
and
14
-
year
follow-up
of
a
patient
diagnosed
with
Papillon-
Lefevre
syndrome
(
PLS
)
.
A
female
child
,
diagnosed
with
PLS
-associated
periodontitis
at
the
age
of
9
years
and
11
months
,
presented
with
hyperkeratosis
of
the
palms
and
soles
,
as
well
as
generalized
aggressive
periodontitis
.
The
dental
treatment
comprised
standard
periodontal
debridement
,
scaling
and
root
planing
,
instructions
on
oral
hygiene
,
restorations
,
extraction
of
hopelessly
affected
teeth
and
a
therapeutic
use
of
antibiotics
.
The
concomitant
supportive
periodontal
therapy
and
antibiotic
coverage
could
not
stop
the
loss
of
periodontal
attachment
and
destruction
of
the
alveolar
bone
.
Four
years
after
treatment
was
initiated
,
the
last
remaining
teeth
were
extracted
and
complete
dentures
were
constructed
.
The
dentures
have
been
periodically
replaced
and
the
patient
continues
to
return
for
follow-up
once
a
year
.
The
combination
of
intensive
periodontal
treatment
and
antibiotic
regimen
only
temporarily
delayed
periodontal
disease
progression
and
did
not
prevent
loss
of
both
primary
and
permanent
teeth
.
The
outcome
of
this
long
-term
follow-up
case
report
shows
that
management
of
PLS
-associated
periodontitis
is
further
complicated
when
the
patient
is
first
seen
in
the
mixed
dentition
stage
or
later
.
In
these
situations
,
the
chances
of
controlling
the
progression
of
periodontal
breakdown
and
minimizing
tooth
loss
are
greatly
reduced
.
Diseases
Validation
Diseases presenting
"hopelessly affected teeth"
symptom
papillon-lefèvre syndrome
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