Rare Diseases Symptoms Automatic Extraction

Papillon-Lefèvre syndrome and squamous cell carcinoma: a case report.

[papillon-lefèvre syndrome]

Papillon-Lefèvre syndrome is a rare autosomal recessive genodermatosis characterised by palmoplantar hyperkeratosis and severe early-onset periodontitis. The development of malignant cutaneous neoplasms within the hyperkeratotic lesions of the syndrome is very rare. Here, we report on a 67-year-old German Caucasian male with Papillon-Lefèvre syndrome associated with recurrent squamous cell carcinoma. Treatment is symptomatic and not always satisfactory.

Diseases presenting "squamous cell carcinoma" symptom

  • carcinoma of the gallbladder
  • child syndrome
  • dystrophic epidermolysis bullosa
  • epidermolysis bullosa simplex
  • esophageal adenocarcinoma
  • esophageal carcinoma
  • esophageal squamous cell carcinoma
  • junctional epidermolysis bullosa
  • kallmann syndrome
  • kindler syndrome
  • liposarcoma
  • monosomy 21
  • oculocutaneous albinism
  • oral submucous fibrosis
  • papillon-lefèvre syndrome

This symptom has already been validated