Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Alteration in plasma lipid profile in oral submucous fibrosis patients: A case control study.
[oral submucous fibrosis]
Lipids
are
major
cell
membrane
components
essential
for
various
biological
functions
including
cell
growth
and
division
of
normal
and
malignant
tissue
.
They
are
also
required
for
maintenance
of
structural
and
functional
integrity
of
all
biological
membranes
.
Alteration
in
the
plasma
lipid
profile
has
been
associated
with
a
variety
of
cancers
and
precancerous
conditions
including
those
of
the
head
and
neck
region
.
The
present
study
aimed
to
evaluate
the
alteration
in
plasma
lipid
profile
in
oral
submucous
fibrosis
(
OSF
)
patients
.
A
total
of
30
patients
were
included
in
the
study
,
20
with
oral
submucous
fibrosis
and
10
healthy
controls
.
Fasting
plasma
lipid
profile
including
Total
Cholesterol
(
TC
)
,
Very
Low
Density
Lipoproteins
(
VLDL
)
,
Low
Density
Lipoproteins
(
LDL
)
,
High
Density
Lipoproteins
(
HDL
)
and
Tri
-
Glycerides
(
TG
)
were
measured
using
semiautomatic
analyser
.
The
data
obtained
were
analysed
using
independent
sample
'
t
'
test
.
A
statistically
significant
decrease
in
plasma
total
cholesterol
,
LDL
and
HDL
was
observed
in
patients
with
OSMF
as
compared
to
the
controls
,
but
it
was
not
statistically
significant
for
VLDL
and
TG
values
.
The
results
of
the
present
study
show
that
there
is
an
inverse
relationship
between
lipid
profile
and
the
presence
of
oral
submucous
fibrosis
.
Hence
,
alteration
in
plasma
lipid
profile
may
have
a
diagnostic
role
in
the
future
and
can
be
used
as
a
biochemical
indicator
to
detect
the
initial
changes
seen
in
the
neoplastic
process
.
Diseases
Validation
Diseases presenting
"ldl and hdl was observed in patients with osmf as compared to the controls"
symptom
oral submucous fibrosis
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom
