Rare Diseases Symptoms Automatic Extraction
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A random Abstract
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Of Omenn and mice.
[omenn syndrome]
Omenn
syndrome
(
OS
)
is
a
peculiar
immunodeficiency
in
which
profound
T
and
B
cell
defects
are
associated
with
severe
autoimmune
manifestations
.
Although
the
molecular
and
biochemical
bases
of
OS
have
been
elucidated
,
the
mechanisms
leading
to
T
cell
infiltration
of
peripheral
tissues
such
as
skin
and
gut
still
remain
unsolved
.
Two
murine
models
with
hypomorphic
mutations
in
rag
genes
reproducing
OS
features
and
a
murine
model
of
lymphopenia
-derived
autoimmunity
with
similar
immunopathology
were
recently
described
.
The
aim
of
this
review
is
to
integrate
clues
regarding
the
roles
of
impaired
thymic
development
and
lymphopenia
into
the
pathogenesis
of
autoimmunity
.
Diseases
Validation
Diseases presenting
"immunodeficiency"
symptom
adrenal incidentaloma
allergic bronchopulmonary aspergillosis
cushing syndrome
dracunculiasis
hirschsprung disease
hodgkin lymphoma, classical
homocystinuria without methylmalonic aciduria
kabuki syndrome
legionellosis
malignant atrophic papulosis
oculocutaneous albinism
omenn syndrome
papillon-lefèvre syndrome
primary effusion lymphoma
primary hyperoxaluria type 1
pyomyositis
severe combined immunodeficiency
sneddon syndrome
werner syndrome
wiskott-aldrich syndrome
wolf-hirschhorn syndrome
x-linked adrenoleukodystrophy
This symptom has already been validated