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Living with orofacial conditions: psychological distress and quality of life in adults affected with Treacher Collins syndrome, cherubism, or oligodontia/ectodermal dysplasia-a comparative study.
[oligodontia]
The
relationship
between
quality
of
life
,
psychological
distress
,
and
orofacial
syndromes
in
children
and
adolescents
has
been
reported
in
several
studies
.
However
,
little
is
known
about
differences
in
psychological
distress
and
quality
of
life
among
adults
with
different
orofacial
conditions
.
Therefore
,
the
aims
of
this
study
were
to
examine
and
compare
these
factors
among
three
groups
of
adults
affected
by
Treacher
Collins
syndrome
(
TCS
)
,
cherubism
,
and
oligodontia
/
ectodermal
dysplasia
(
ED
)
.
We
included
11
individuals
with
TCS
(
mean
age
46
.
9
,
SD
12
.
9
Â
years
)
,
15
with
cherubism
(
mean
age
50
.
3
,
SD
16
.
8
Â
years
)
,
and
49
with
oligodontia
/
ED
(
mean
age
30
.
7
,
SD
15
.
6
Â
years
)
.
The
respondents
completed
questionnaires
related
to
psychological
distress
and
quality
of
life
.
The
oligodontia
/
ED
group
had
a
significantly
higher
level
of
anxiety
and
worse
mental
health-related
quality
of
life
than
both
the
TCS
and
cherubism
groups
.
Adults
with
TCS
reported
the
highest
level
of
depression
,
and
the
lowest
levels
of
overall
quality
of
life
,
well-being
,
and
physical
health-related
quality
of
life
.
The
cherubism
group
displayed
the
best
overall
quality
of
life
,
well-being
,
and
mental
health
.
Psychological
distress
and
quality
of
life
differed
in
various
orofacial
conditions
.
This
study
provided
insight
into
these
aspects
that
may
contribute
to
improved
care
.
Diseases
Validation
Diseases presenting
"physical health-related quality"
symptom
oligodontia
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