Severe megacystis and bilateral hydronephrosis in a female fetus.

[megacystis-microcolon-intestinal hypoperistalsis syndrome]

The differential diagnosis for antenatal bladder dilation and hydronephrosis is extensive , ranging from posterior urethral valves to neurogenic bladder . We present a case of a female fetus diagnosed antenatally with severe megacystis and bilateral hydroureteronephrosis . The patient was found to have megacystis-microcolon -intestinal hypoperistalsis syndrome , a rare , congenital , and generally fatal disorder in which there is functional obstruction of the bladder and intestine .