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Myelomalacia and hypoglycorrhachia in malignant atrophic papulosis.
[malignant atrophic papulosis]
A
25
-
year
-old
man
with
the
skin
lesions
of
malignant
atrophic
papulosis
had
clinical
and
electrodiagnostic
evidence
of
a
multifocal
asymmetric
myelomalacia
or
polyradiculopathy
in
association
with
elevated
CSF
protein
and
hypoglycorrhachia
.
Autopsy
findings
included
widespread
infarctions
and
necrosis
of
brain
,
brainstem
,
and
spinal
cord
.
The
combined
clinical
and
laboratory
findings
were
similar
to
those
seen
in
systemic
lupus
erythematosus
,
sarcoidosis
,
or
meningeal
carcinomatosis
.
Thus
,
malignant
atrophic
papulosis
should
be
added
to
the
differential
diagnosis
of
either
polyradiculopathy
or
myelomalacia
.
Diseases
Validation
Diseases presenting
"skin lesions"
symptom
child syndrome
cowden syndrome
cutaneous mastocytosis
cystinuria
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
erdheim-chester disease
erythropoietic protoporphyria
familial mediterranean fever
focal myositis
gm1 gangliosidosis
heparin-induced thrombocytopenia
hirschsprung disease
junctional epidermolysis bullosa
lamellar ichthyosis
liposarcoma
lymphangioleiomyomatosis
malignant atrophic papulosis
oligodontia
omenn syndrome
papillon-lefèvre syndrome
primary effusion lymphoma
proteus syndrome
severe combined immunodeficiency
sneddon syndrome
waldenström macroglobulinemia
werner syndrome
wiskott-aldrich syndrome
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