Myelomalacia and hypoglycorrhachia in malignant atrophic papulosis.

[malignant atrophic papulosis]

A 25 -year -old man with the skin lesions of malignant atrophic papulosis had clinical and electrodiagnostic evidence of a multifocal asymmetric myelomalacia or polyradiculopathy in association with elevated CSF protein and hypoglycorrhachia . Autopsy findings included widespread infarctions and necrosis of brain , brainstem , and spinal cord . The combined clinical and laboratory findings were similar to those seen in systemic lupus erythematosus , sarcoidosis , or meningeal carcinomatosis . Thus , malignant atrophic papulosis should be added to the differential diagnosis of either polyradiculopathy or myelomalacia .

Diseases
Validation

Diseases presenting "systemic lupus erythematosus" symptom

acute rheumatic fever

familial mediterranean fever

focal myositis

hodgkin lymphoma, classical

inclusion body myositis

malignant atrophic papulosis

oligodontia

papillon-lefèvre syndrome

primary hyperoxaluria type 1

pyomyositis

sneddon syndrome

werner syndrome

x-linked adrenoleukodystrophy

This symptom has already been validated