Rare Diseases Symptoms Automatic Extraction

Malignant atrophic papulosis. A report of two cases with altered fibrinolysis and platelet function.

[malignant atrophic papulosis]

Malignant atrophic papulosis is a systemic vaso-occlusive disorder characterized by typical skin lesions. We report two new cases with impairment of blood fibrinolytic activity and alterations in platelet function. The first case showed an increase in plasminogen activator inhibitor-1 (PAI-1) activity, and the second case had a decrease in platelet aggregation induced by adenosine diphosphate and adrenaline but normal with collagen. The impairment of blood fibrinolytic activity and platelet aggregation may have pathogenic and therapeutic implications in malignant atrophic papulosis.

Diseases presenting "second case" symptom

  • allergic bronchopulmonary aspergillosis
  • canavan disease
  • coats disease
  • cutaneous mastocytosis
  • esophageal adenocarcinoma
  • fabry disease
  • holt-oram syndrome
  • junctional epidermolysis bullosa
  • legionellosis
  • malignant atrophic papulosis
  • omenn syndrome
  • pleomorphic liposarcoma
  • primary hyperoxaluria type 1
  • proteus syndrome
  • von hippel-lindau disease
  • well-differentiated liposarcoma
  • werner syndrome
  • wolf-hirschhorn syndrome
  • x-linked adrenoleukodystrophy

You can validate or delete this automatically detected symptom